This means taking your dose either 1 hour before eating or 2 hours after eating. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. Generics tend to cost less than brand-name drugs. CellCept is available in other forms, including a liquid that you swallow and an infusion thats given by a healthcare professional. In this situation, your doctor may give you the CellCept infusion for up to 14 days. The capsule forms of both drugs are typically taken twice per day. There are 6 disease interactions with CellCept (mycophenolate mofetil) which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. If you stop taking CellCept suddenly, you may have a serious side effect called organ rejection. These include foods that are high in sugar, unhealthy fats, and alcohol as well as several others listed above. These lists contain up to 10 of the most common mild side effects that can occur with each drug, or with both CellCept and Prograf (when taken individually). The IV infusion should be given within 24 hours of a transplant. CellCept is an immunosuppressant (a drug that weakens your immune system). * Organ rejection occurs when the immune system attacks a transplanted organ. While outdoors, wear a broad-spectrum sunscreen with a high protection factor. Enter other medications to view a detailed report. In clinical studies, certain side effects occurred more often in children who took CellCept than in adults. Possibly. CellCept has a boxed warning for the risk of congenital anomalies and pregnancy loss. These serious infections can include: Call your doctor right away if you have any of the following signs and symptoms of infection: SeeWhat are the possible side effects of CellCept?for information about other serious side effects. They can discuss with you the risks and benefits of continuing your CellCept treatment. Especially tell your doctor if you take: Know the medicines you take. Promptly consult your doctor or pharmacist. The CellCept dosage your doctor prescribes will depend on several factors. CellCept and Myfortic are both brand-name drugs. Do not take 2 doses at the same time. Here are 11 foods to limit when you're trying to lose weight. Prednisone can also cause a redistribution of fat to the face, back of the neck and the abdomen, although these changes vary from person to person. Serious inflammatory response, which can develop weeks to months after starting treatment or after a dosage increase. Minimally clinically significant. They may be temporarily stored at temperatures of 59F to 86F (15C to 30C), such as when traveling. (Skin spots may be discolored, scaly, or crusty.). Before taking CellCept, talk with your doctor about your health history. Increased risk of getting certain cancers. Both drugs were given with corticosteroids and cyclosporine (Neoral). Anemia (low number of red blood cells) may happen while taking CellCept. (Having a stable transplant means you arent experiencing any symptoms of organ rejection. A pregnancy registry helps gather information on how certain drugs can affect pregnancy. Capsules should be stored at room temperature. Yes, CellCept may be used off-label to treat lupus. Some vaccines may not work as well during treatment with CellCept. A boxed warning is the most serious warning from the Food and Drug Administration (FDA). Serious side effects and their symptoms can include: * For more information on these side effects, see Side effect details below. Please see fullPrescribing Information,including Boxed WARNINGS and Medication Guide, for additional Important Safety Information. Minor multivitamins with minerals mycophenolate mofetil Minor Drug Interaction Information for this minor interaction is available on the professional version. The link you have selected will take you away from this site to one that is not owned or controlled by Genentech, Inc. Genentech, Inc. makes no representation as to the accuracy of the information contained on sites we do not own or control. Prograf is available as a generic drug called tacrolimus. It is an immunosuppressant drug that tamps down the immune system and helps to prevent organ rejection. Therefore, this information was not gathered in a clinical study overseen by researchers. If youre taking a form of CellCept thats swallowed, in most cases you should take it on an empty stomach. In clinical studies of adults, CellCept was compared with azathioprine (Azasan, Imuran) and a placebo (a treatment with no active drug). You should understand how the drug affects you before driving. CellCept and Myfortic have some similar side effects and others that vary. (Scleroderma is a condition that affects the bodys skin and tissues.) This happens because the immune system doesnt recognize the new organ as part of your body. Possible symptoms of infection include: In clinical studies of adults, CellCept was compared with azathioprine (Azasan, Imuran) and a placebo. Prograf contains the active ingredient tacrolimus. If you have questions about using CellCept with antacids, talk with your doctor. A live vaccine contains a weakened form of the virus or bacteria that it helps prevent infection from. Prograf injection should be discontinued as soon as you are able to take the oral form of Prograf. Youll likely take CellCept twice per day. Promptly consult your doctor or pharmacist. *) Talk with your doctor about whether or not your condition is stable enough to take this drug with food. To decrease your risk for skin cancer while using CellCept, you should limit your time spent in the sun. Taking CellCept may cause unexplained weight loss. This is because drinking alcohol can lead to health problems that cause extra strain on your transplanted organ, such as hypertension (high blood pressure). Your . These infections may lead to serious outcomes, including the need to be hospitalized, and even death. Tablets should be stored at room temperature (77F/25C) in a tightly sealed container away from light. However, this drug hasnt been studied in breastfeeding people. Read More. Stem cell transplants currently treat some cancers and blood and immune disorders. It can be prescribed after a heart, kidney, or liver transplant in combination with other immunosuppressant drugs. A boxed warning is the most serious warning from the FDA. How does blood work, and what problems can occur? (Phosphate is a chemical that naturally occurs in the body.). Granulocyte colony stimulating factor (G-CSF) is a type of drug that doctors prescribe to manage neutropenia. Call your doctor right away if you have serious side effects. by visiting the Risk Evaluation and Mitigation Strategy (REMS) website at, unexplained fever, prolonged tiredness, weight loss or lymph node swelling, a brown or black skin lesion with uneven borders, or one part of the lesion does not look like the other, shingles, other herpes infections, and cytomegalovirus (CMV). You should take it for as long as your doctor decides its safe and effective for you. CellCept may influence your ability to drive and use machines (See, blood problems including low white and red blood cell counts, swelling of the lower legs, ankles and feet, changes in laboratory blood levels, including high levels of blood sugar (hyperglycemia), stomach problems including diarrhea, constipation, nausea and vomiting, nervous system problems such as headache, dizziness and tremor. If you miss a dose of CellCept, or you are not sure when you took your last dose, take your prescribed dose of CellCept as soon as you remember. If you have a lighter skin tone or a family history of skin cancer, your risk of getting skin cancer while using CellCept may be even higher. We comply with the HONcode standard for trustworthy health information. The following information is provided for clinicians and other healthcare professionals. These include: Note: For more information about the potential negative effects of CellCept, see the CellCept side effects section above. A change in your diet, medicine, or dosage may be necessary. Examples of birth control pills that contain levonorgestrel include Seasonique and Twirla. It can be prescribed after a heart, kidney, or liver transplant with other immunosuppressant drugs. If you have questions about using CellCept for the treatment of myasthenia gravis, talk with your doctor. Hepatitis viruses can affect how your liver works. Before you start using CellCept, be sure to tell your doctor if you take any PPIs. However, if you do have any of these symptoms, tell your doctor right away so they can treat your condition. Heres some detail on certain side effects this drug may or may not cause. CellCept is FDA-approved to help prevent organ rejection after a heart, kidney, or liver transplant in combination with other immunosuppressants. If you drink alcohol and have questions about drinking alcohol while using CellCept or after having an organ transplant, talk with your doctor. This means taking your dose either 1 hour before eating or 2 hours after eating. Severe Interactions These medications are not usually taken together. CellCept is available in the following forms and strengths: The first oral dose of CellCept is given as soon as possible after a kidney, heart, or liver transplant. CellCept is FDA-approved to help prevent organ rejection in children ages 3 months and older. If you have not told your doctor about any of the above, do so before you start taking CellCept. Take this medication by mouth as directed by your doctor, usually twice daily on an empty stomach, 1 hour before or 2 hours after meals.. Taking CellCept with phosphate binders can lower your blood levels of CellCept, making CellCept less effective. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. It works by preventing immune cells from multiplying. This can lead to side effects from the chemotherapy drug. Avoid storing this medication in areas where it could get damp or wet, such as bathrooms. It isnt known how many people who used a placebo may have had depression. Using CellCept in children ages 3 months and older for this purpose is supported by information from clinical studies of adults who have had a heart transplant. They may also recommend treatments to help with your depression. Take this medication by mouth with or without food as directed by your doctor, usually once daily. However, if its within 2 hours of when youre supposed to take your next dose, just skip the missed dose. This extra fluid in your body can make it seem like youve gained weight. * Some may be a better fit for you than others. are pregnant or plan to become pregnant. If you are a female . If you throw up after: less than 30 minutes: repeat the full mycophenolate dose (repeat the dose only once) more than 30 minutes: do not repeat the dose Prograf is also available in granules that are mixed with water to form a liquid that you swallow. Its also supported by additional data from use in children. Researchers wanted to see how effective each treatment was at preventing treatment failure. 2023 Genentech USA, Inc. All rights reserved. Tell your doctor if you have: Increased risk of getting serious infections. Then take your next dose at its usual time. To learn about using Prograf in children, talk with your childs doctor. You can also refrigerate the liquid at temperatures of 36F to 46F (2C to 8C). Available for Android and iOS devices. Drink ice-cold or clear drinks (for example, unsweetened tea or water) Avoid foods that are sweet, greasy, or fried. Sharing this information can help you avoid potential interactions. Pregnancy tests should be repeated and discussed with your doctor routinely during follow-up visits. Possibly. Receiving this medicine while you are pregnant can harm your unborn baby. Side effects that were more common in children include: For more information on these side effects, see the Mild side effects and Serious side effects sections above. You also shouldnt donate semen while taking this drug. Do not freeze the medication. Both CellCept and Myfortic are available as tablets that you swallow. Generally speaking, the higher the dose and the longer the treatment, the greater the changes. have Phenylketonuria (PKU). They can recommend a different treatment for your condition. Before you start CellCept, tell your doctor about any medications youre taking. prednisone, triamcinolone, prednisolone, tacrolimus, azathioprine, cyclosporine, mycophenolate mofetil, cyclophosphamide, cortisone, Imuran. Both drugs belong to a group of medications called immunosuppressants (drugs that weaken your immune system). Your childs doctor will know how to calculate your childs body surface area to determine the correct dose. Eat smaller meals. Food affects how the body absorbs mycophenolate. Taking CellCept with food. The results showed that: The percentage of adults who had anemia after taking these drugs varied depending on the condition being treated. Taking CellCept may increase your risk for certain types of cancers, including lymphoma (a type of cancer that starts in your white blood cells) and skin cancer. However, live vaccines could cause infections in people whose immune systems are weakened, including those taking immunosuppressants such as CellCept. The typical dosage of CellCept for preventing rejection of a heart transplant is 1,500 mg taken twice per day. Do not cut, crush, or chew the medicine. Blood and urine tests may be needed to check for unwanted effects. Both types of infusions are given by your doctor. To give an example, for a child whose body surface area is 1.25 m2, the typical dose is 750 mg taken twice per day. Your doctor will likely check your red blood cell count before you start using CellCept. The most common side effects of CellCept include: Side effects that can happen more often in children than in adults taking CellCept include: These are not all of the possible side effects of CellCept. You may wonder how CellCept compares with other medications that are prescribed for similar uses. According to the manufacturer, Novo Nordisk, people who are taking Ozempic and experience nausea should consider doing the following: Eat slowly. Its approved for use in adults and children ages 3 months and older. . However, as soon as youre able to swallow CellCept capsules, tablets, or liquid, your doctor will likely stop giving you the infusion form. For more information, see the CellCept dosage section below. Each infusion is given by your doctor over a period of about 2 hours. Examples of antacids that contain magnesium hydroxide or aluminum hydroxide include: To lower the risk of this interaction, its recommended that you take antacids at least 2 hours after your dose of CellCept. The Food and Drug Administration (FDA) approves prescription drugs such as CellCept to treat certain conditions. Of the total drug interactions, This can raise your risk for side effects from drugs that are cleared through kidney tubules. This can make CellCept less effective. This happens because the immune system doesnt recognize the new organ as part of your body. Both CellCept and Prograf are available as capsules that you swallow and as an intravenous (IV) infusion* (an injection into a vein over a period of time). Steer clear of inflammatory foods such as grains and legumes, nightshades, gluten, and dairy. Common sweetener erythritol tied to higher risk of stroke and heart attack, Gout: How metabolic syndrome may increase the risk, A new therapeutic target for the prevention of heart failure due to aortic stenosis, Skipping breakfast and fasting may compromise the immune system, What to know about granulocyte colony stimulating factor (G-CSF), All about hematopoietic stem cell transplantation, Stem cell therapy for rheumatoid arthritis. Some people may experience a rash while taking CellCept. Symptoms can include: discoloration, heat, pain, or swelling in the infected area, 27.4% to 39.9% of adults who were given CellCept had an infection, 24.9% to 33.7% of adults using azathioprine had an infection, 37.3% of adults using a placebo had an infection, 0.4% to 1% of adults developed a type of lymphoma (depending on the condition being treated), 1.35% of children developed a type of lymphoma, 1.6% to 4.2% of adults developed skin cancer, 0.7% to 2.1% of adults developed other types of cancer, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, 20.1% of adults who were given CellCept after a heart transplant had depression, 15.2% of adults who were given azathioprine after a heart transplant had depression, loss of interest in activities you once enjoyed, trouble concentrating or making decisions, 26% of adults who used CellCept had a rash, 20.8% of adults who used azathioprine had a rash, 20% to 45% of adults who used CellCept had anemia, 23.6% to 53% of adults who used azathioprine had anemia, 2.4% of adults who used a placebo had anemia, 32% of adults who used CellCept experienced an organ rejection, 35% of adults who used azathioprine experienced an organ rejection, 6.2% of adults who used CellCept required a new heart transplant or died, 11.4% of adults who used azathioprine required a new heart transplant or died, 38.5% of adults who used CellCept experienced an organ rejection, 47.7% of adults who used azathioprine experienced an organ rejection, 14.7% of adults who used CellCept required a new heart transplant or died, 14.6% of adults who used azathioprine required a new heart transplant or died, stopping the study early for any reason other than organ rejection, 30.3% to 38.8% of adults using CellCept experienced treatment failure, 47.6% to 50% of adults using azathioprine experienced treatment failure, 56% of adults using a placebo experienced treatment failure, 2% of children died while receiving CellCept for their kidney transplant, the type of organ transplant youre using CellCept for, capsules, available in one strength of 250 milligrams (mg), tablets, available in one strength of 500 mg, liquid that you swallow, available in one strength of 200 mg per milliliter (mL) of liquid, a maximum dose of 3,000 mg daily or 15 mL of oral suspension daily, a maximum dose of 2,000 mg daily or 10 mL of oral suspension daily, serious inflammatory reaction which may cause fever, joint pain, joint stiffness, and muscle pain, numbness or tingling in your hands and feet, low levels of magnesium and phosphate in your blood, QT prolongation (a change in the electrical activity of your heart), myocardial hypertrophy (a certain heart problem), aluminum hydroxide/magnesium carbonate (Gaviscon), aluminum hydroxide/magnesium hydroxide/simethicone (Mylanta), fluoroquinolones, such as levofloxacin (Levaquin), capsules, tablets, and liquid that you swallow. 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Sugar, unhealthy fats, and dairy Interaction is available on the professional version occurs when the immune )... Example, unsweetened tea or water ) avoid foods that are prescribed for similar uses CellCept to certain... Often in children, talk with your doctor routinely during follow-up visits medication records CellCept treatment systems are,... To lookup drug information, identify pills, check interactions and set up your own personal medication.. Drug called tacrolimus youre supposed to take the oral form of prograf and even death spent the...