IVF#5 July 2010 - will be using estrogen priming For this reason, the antagonist protocol is a good option for those women most susceptible to OHSS. Fortunately, there are a few steps you can take to prevent and. 5-7 oz Orange, mid season). Right ovary has 2-4 follies<12mm. I have hypothalamic anvolution, DH normal. One thing to keep in mind is that every cycle, there is a new cohort of follicles availble to be stimulated, meaning that during different months the same protocol may work more successfully than others simply due to the natural variation in available follicles. Spandorfer said it would not suppress me to much not sure about this, need to speak with him further. Avery & Sydney born June 12/11 at 30w1d. Very helpful! Thanks so much! So.. My dr prescribed Lupron Flare protocol with 300 Follistim, 150 Menopur, and 20 Lupron daily. I have AMH of 0.1 or something like that. The last cycle, I was able to produce 10 eggs but only 2 made it to transfer. Oh yeah that could have been it or a combo! The deadline for sending in seeds was October 15th, but there are still plenty of ways to get involved. I have my appt in a few hours. I imagine the Follistim is lowered partly to keep the egg number from increasing (had OHSS w/IVF #1). By and large there are two easy ways to think about protocols: how much gonadotropin (the drug that prompts follicles to grow) gets used, and what other drugs get used alongside the gonadotropin which is typically what defines a given protocol strategy. Went to retrieval anyway, did ICSI, but it didn't fertilize. Was one of my worst cycles. MENTS: This time around I did estrogen priming and the results of my day 5 ultrasound were disappointing (8 follicles, with an E2 level of 98.6) and now at day 7 they are worse (2 of the smaller follicles haven't budged in size so only 6 seem to be in the game but 3 are leading). The goal was to use the estrogen to prevent any dominant follicles from taking over again to allow follicles to grow evenly. I understand the idea for the patch is to help time the growth of follicles vs. increase the number? Best of luck x Reply Quote (51.2% vs 25%; p = 0.047) were noted. That could be bogus, but it makes sense, right? Some reproductive endocrinologists will change the treatment strategy based on the number of follicles available at the start of the cycle. They studied what happens when you replace gonadotropin with clomid (a cheaper, less potent alternative) for a few days before the retrieval. February 7 - lost our little twin, Baby B had no heartbeat at 20 weeks, June 8, 2011 - DD was born healthy and her twin brother was born to Heaven. Looking for info/success stories with Estrogen priming protocol with DOR. Please whitelist our site to get all the best deals and offers from our partners. Interesting that they are only putting you on it for 7 days.. If ok, then start stimulation The many repeat bloodworks & ultrasoundsLast stimulation shot + triggerRetrievalSo I started my process in the mid-September and my retrieval happened in early NovemberAlso, I was on MicroFlare protocol, so I am not sure what other medications you might be taking. (Not so) Short summary - DH and I have been ttc since May 2015, two early m/c. The results are below and as you can see, success rates do seem to drop off after 300 IUs per day of gonadotropin. The misoprostol was not expensive; on average, it's about $30. Estrogen Priming is completely different, so therefore without birth control pill.I would ask your doctor, but I guess you just do nothing while preparing for the cycle. For patients with a healthy ovarian reserve such a long stretch of ovulation suppression is often not a problem. I did estrogen priming and human growth hormone with IVF#2 if you compare the cycles, it actually seems like the second cycle was worse!! I was in the April but had a cyst on ultrasound prior to starting meds so had to cancel the plans. How many follicles were you usually starting with? Collection was yesterday and they retrieved 9 eggs. Some people think having too much of the FSH meds is harmful for quality (and also so expensive of course). Implantation Calendar: What is Happening During the Two Week Wait. I hope you like the protocol. Please specify a reason for deleting this reply from the community. For my cycle in July they are not giving me Lupron but are giving me Antagon. It's not the same for everyone over 40. DOR women often get over suppressed by BCP; my doctor uses it as a rule for DOR. Cetrotide was added CD9. These drugs signal to the brain not to instigate ovulation. Johns Hopkins School of Medicine, Medical Director, REI He also said he would start with BCPs to suppress ovulation- he explained why, but at my age that just doesn't sound like a good idea to be suppressing anything. I have AMH of 0.1 or something like that. HI.. hope all is well. I think it helped keep my follicles all around the same size so that I didn't end up with some over-mature eggs and some under-mature eggs at retrieval. I am 38. On CD2 I started 300 Gonal F and 150 Menopur. My dr said if we try again she would use the same protocol as there is no magic protocol for poor responders. Ideally, between 15 - 20 mature eggs would be retrieved, though getting a number that high is uncommon. Good Morning. It is used for low/poor responders -- often women with high FSH and/or over 35 years of age. However other had mature egg and we did Icsi by it didn't grow from there. Cool.let me know what he says if you would please. Below is data collected on over 3,000 cycles for each protocol approach in the Netherlands. Estrogen priming has worked both times for me. . This is the oldest IVF protocol and is especially effective in preventing premature ovulation during the cycle. I am about to embark on my IVF#6 cycle (1st time at CCRM)- I've always done OCP/BCP before my IVF stim cycle(antagonist) and have produced between 15-19 eggs each time. Heres an example from the same study. I felt icky too the first day of starting estrace but I think it's also because they put me on a zpac to kill any infections and that made me sick my fingers are crossed that your period doesn't come and you can start cycling. I think you both are at Cornell (were) with this estrogen priming protocol will you try again with them, and request not to do estrogen priming? Experience with Estrogen Priming Protocol? This is standard practice when ordering from Ukraine, according to customers wh. Was wondering since your AMH was good and FSH, why did they recommend the Estrogen priming protocol for you? We're banking this cycle and testing them with the biopsies from the next. Those 2 were my worst cycles. I just want to be knowledgeable and advocate for myself bc like many others on here, being over 40 I there's no time to waste-. As you can see below, success rates dropped. 05/18/2018 23:18 Subject : Protocol . They said that they look at FSH less now as they find it too unreliable. Often two other types of drugs are needed to accompany gonadotropin: those that block eggs from maturing and being ovulated before they can be retrieved, and those that help trigger the eggs to mature so they can be retrieved. Just devastated with my results today so just want to cry it out and then I will respond to you. The dose of gonadotropin matters because, generally speaking, if too little is prescribed, too few eggs are retrieved, and IVF success rates go down. Also, your stims are actually a lot higher than most REs will do for DOR. My friends did this estrogen priming protocol and highly recommend it and were successful. Inhibin is an often overlooked hormone which suppresses (or inhibitits) the release of FSH from your brain during the last week of the cycle (FSH is the chief hormone responsible for making your eggs "grow"). I was on BCP for 15 years and when I went off them I never got my period. Specifically, poor responders (a less than pleasant way of referring to women who produce few eggs per retrieval), do equally well taking 150 IUs of gonadotropin as 450 IUs. IVF#1 with ICSI spring 2006 - 3 eggs retrieved, one transferred - BFN Get Ready for a New Season of Gardening -Choose from Tomatoes, Peaches, Corn, Zinnias & More! Will let you know how things go from here. 2 Girls!! The protocol can also be preceded by the use of BCPs even if you have DOR. After 2 years, tons of tests and 5 IVF cycles, it still feels unreal.Estrogen Priming protocol does not have birth control pills. This is my first time posting and was hoping for some other stories like mine. Estrogen priming is a protocol used during in vitro fertilization (IVF) to facilitate a more gradual and coordinated growth of follicles in the ovary in women with diminished ovarian reserve (DOR). I was long Lupron and that one was cancelled because my precious RE only saw very few follies. TTC with DOR (Diminished Ovarian Reserve), the most helpful and trustworthy pregnancy and parenting information. The Antagonist protocol uses Lupron as its trigger, rather than hCG, and Luprons properties dramatically lower the risk a woman will hyperstimulate. - Longdom | Contributor. Patients undergoing a MFP required more injections (40 vs. 26) than an EPP and spent an average of $4,375.00 compared to EPP patients who spent $5,485.00. I did that back in the beginning of the year but I ovulated in my own and terrified it might happen again. Before gonadotropin is taken there is reason to believe that if a woman is given androgens like testosterone (often in patch form or gel form), it will help her follicles respond to gonadotropin. However, that information will still be included in details such as numbers of replies. It helps your lining and encourages your eggs to all grow at the same rate. No, IVF 5 was the estrogen priming. Hi there. It's hard for me to say definitively because I haven't had wtf yet. I dont know as much about micro flare. This was all on the phone, so not 100 percent on what the protocol would be. Sign up now for your monthly dose of fertility info, experiences, and insight. For many gardeners, it starts with tomatoes. Estrogen priming is typically done for about seven days before the start of controlled ovarian stimulation (the IVF cycle). I'm struggling not to blame myself as my husband's swimmers are per. There are two downsides to this protocols: The long duration of injections (they start the previous cycle) and. Please select a reason for escalating this post to the WTE moderators: Connect with our community members by starting a discussion. Before starting the pills, we need to wait until you are in the correct stage of your menstrual cycle (the luteal phase). Buy Organic Seeds Risk Free From Organic Seeds TOP - Credit Card & Western Union Payment Options, Organic Seeds TOP is a seed vendor based in the Ukraine. Is a micro-dose lupron protocol considered a low-dose protocol? As you may recall in the Revelli and Yousef studies, 150 IUs per day of gonadotropin were used, which is well higher than most things marketed as mini-stimulation approaches, and any natural (no gonadotropin) approach. Recently went thru an IVF cycle that gave me a poor result: 3 blasts all abnormal.RE suggested BCP for 21 days followed by lupron. Thus, for those most concerned with OHSS (like women with PCOS or high AFC or AMH), this can be an inferior option. Below is a meta-analysis of 17 (relatively small) studies that, taken together, show the strategies have nearly identical pregnancy rates. Are you sure you want to block this member? 2nd IVF/ICSI age 42 : Menopur 425; 2 eggs; 2 fertislised; transfer day 5; BFN Group Leaders arent expected to spend any additional time in the community, and are not held to a set schedule. You are posting as a Guest without being logged in. Today, were seeing more well-respected doctors choosing to compliment lower dose of gonadotropin with clomid or letrozole in this group. This website uses cookies for functionality, analytics and advertising purposes as described in our. Had three chromosomal miscarriages last year, moved on to IVF with intention of genetic testing but had to cancel cycle a few days in, E2 never got above 36 while on max dose of 300 Gonol f and 300 Menopur. I asked my local RE about it, but she wasn't familiar enough with it to try. Hottest Topics -- Last 30 Days I starts on day 1 of my cycle for 25-26 days of estrace.. Not sure why.. undefined will no longer be visible to you including posts, replies, and photos. One well regarded study determined that amongst most IVF patients, those taking over 150 IUs per day of gonadotropin had higher rates of success than those who took less. We're also doing PGS. Gardening, outdoors, country living, my furbabies, my DH, anything but working! They suppress leading up to your cycle so that when you start the meds you get a group of follicles to grow together. Waft really helped was upping gonal f and removing menopur. Thanks for sharing. Babies due June 26, 2011 From NE Ohio to North Central Mississippi, everyone has their own ideas and preferences for what they will plant this year. . If you did it did you have success, what is your situation, did you do pills or patches and for how long, etc.? Best of luck to you. More than I wanted, I think! Did not cover diagnostics like doppler test (40 copay but insurance might have covered this), communicable testing ($400 per person), and specialty meds . It's a sort of "slow burn" methodology the hope being that they slow you way down and protect egg quality while allowing you to stim longer. 6 responded, 5 retrieved, 3 fertilized normally, put all 3 back in at 3dpt - I am currently 27 weeks with one baby girl. i read everywhere it's for "poor responders". Hi. Priming is used to improve the number of mature eggs that can be obtained during the process. Please enable JavaScript in your browser to load the challenge. We're not even 100% sure we are staying with my current clinic but I wanted to research ahead of time either way. Ultimately, for only a handful of patient types has one protocol shown itself to be superior to the others and we profile those below. It was day 3 of my period. 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