0000126319 00000 n A place where you can ask veterinary medicine related questions and get advice from veterinary professionals. If skin or eye irritation occurs or in case of accidental ingestion, seek medical advice immediately and show the label to the physician. Remeron (mirtazapine)." Avoid contact with the treated area for two hours after administration. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. O 0, 3. _YE{-gFYEuPAYEuPAgu0P#l`62f#l`62f#xNd,_- NpmbK.]>0 WebMirataz (mirtazapine transdermal ointment) is a white to off-white ointment containing 2% (w/w) of mirtazapine suitable for transdermal (topical) administration. She was very sick for a few months, going from normal adult healthy to geriatric sensitive kitty over that time. Do not give OP specific treatment instructions, including instructions on meds and dosages. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. Typically, beyond monitoring your pets response to mirtazapine, no specific monitoring is required, but your veterinarian may recommend routine testing depending on your pets' individual needs, other medications they may be on and/or the issue that initially caused your pet to be placed on this medication. Create an account to follow your favorite communities and start taking part in conversations. Protective equipment is not to be worn outside the work area (e.g., in common areas or out-of-doors). Mirtazapine is not approved for use in pediatric patients.. The questions - Sometimes when her appetite drops off, I give her Mirataz and it kickstarts her eating. Do not use mirtazapine with buspirone (Buspar), fentanyl (Abstral, Duragesic), lithium (Eskalith, Lithobid), tryptophan, St. John's wort, or some pain or migraine medicines (eg, rizatriptan, sumatriptan, tramadol, Frova, Imitrex, Maxalt, Relpax, Ultram, Zomig). There are natural alternatives for pet parents looking to stimulate their cat's appetite. Upon stopping mirtazapine transdermal ointment (Mirataz), it is very important to monitor your pet's food intake. She was very sick for a few months, going from normal adult healthy to geriatric sensitive kitty over that time. Agitation and gastrointestinal effects like vomiting may be seen in about 25% to 33% of cats. Cerner Multum, Inc. "UK Summary of Product Characteristics." Mirtazapine is used in cats and dogs to treat unwanted weight loss caused by various conditions, such as liver, kidney, or stomach disease, where a lack of appetite and nausea work hand in hand to decrease food intake. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Do not give possible diagnoses that could explain the symptoms described by OP. Mirataz is the first and only FDA-approved transdermal medication for the management of weight loss in cats. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. For non-prescription products, read the label or package ingredients carefully. Check with your doctor before taking any of the above while you are taking this medicine. Follow your doctor's orders or the directions on the label. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, mood or mental changes, including abnormal thinking, agitation, anxiety, confusion, and feelings of not caring, mood or mental changes, including anger, feelings of being outside the body, mood swings, and unusual excitement, seeing, hearing, or feeling things that are not there, red skin lesions, often with a purple center, sores, ulcers, or white spots on the lips or in the mouth, dizziness or fainting when getting up suddenly from a lying or sitting position, sense of constant movement of self or surroundings, Painful or prolonged erection of the penis, swelling of the breasts or unusual milk production. Applies to mirtazapine: oral tablet, oral tablet disintegrating. We wont go back to the vet unless something significant comes up to solve; my long term very says we need an internist or neurologist for any further treatment. WebThe most common adverse effects reported to the ASPCA Animal Poison Control Center in 84 cats intentionally or accidently exposed to oral mirtazapine included vocalization, agitation, vomiting, abnormal gait/ataxia, restlessness, tremors/trembling, hypersalivation, tachypnea, tachycardia, and lethargy. endstream endobj 527 0 obj <>/Filter/FlateDecode/Index[20 478]/Length 38/Size 498/Type/XRef/W[1 1 1]>>stream 0000022537 00000 n Check with your doctor immediately if any of the following side effects occur while taking mirtazapine: Some side effects of mirtazapine may occur that usually do not need medical attention. This may help prevent a possible worsening of your condition and reduce the possibility of withdrawal symptoms such as headache, nausea, or a general feeling of discomfort or illness. If you would like to report a suspected adverse reaction or product-related issue, please call (866) 683-0660. Mirtazapine may cause some teenagers and young adults to be agitated, irritable, or display other abnormal behaviors. Some side effects may not be reported. Continue reading for a comprehensive list of adverse effects. We comply with the HONcode standard for trustworthy health information. Mirtazapine may cause drowsiness, trouble with thinking, or trouble with controlling body movements. Review/update the Your pets condition worsens or does not improve with treatment, You have additional questions or concerns about the use of mirtazapine. 16, female, spayed, 8.5lbs, clean labs now, but 6 moths ago elevated liver levels and ~3 months of frequent vet visits including clear ultrasound. WebSome side effects include elevated blood pressure and heart rate, vocalization, vomiting, agitation, and restlessness. Mirtazapine can also be used to counteract weight loss caused by chemotherapy. Mirataz should not be given in combination, or within 14 WebSome side effects include elevated blood pressure and heart rate, vocalization, vomiting, agitation, and restlessness. Mirtazapine for cats and humans also has an antiemetic influence , and it is probably due to an antagonist effect on the 5-HT3 receptor linked to vomiting. The most common side effect is drowsiness. You may report side effects to the FDA at 1-800-FDA-1088. Body protection: Not Available Other protection: Wash hands in the event of contact with mixture, especially before eating, drinking or smoking. 0000020124 00000 n There are natural alternatives for pet parents looking to stimulate their cat's appetite. Step 2: Apply even pressure on tube and squeeze a 1.5-inch line of ointment onto your gloved nger using the measured line on the carton or in this package insert. Mirtazapine comes in pill form and is given orally (by mouth). No vet writer or qualified reviewer has received any compensation from the manufacturer of the medication as part of creating this article. information highlighted below and resubmit the form. If you would like to report a suspected adverse reaction or product-related issue, please call (866) 683-0660. %%EOF He may vocalize more than normal and become hyperactive. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. + If you or your caregiver notice any of these unwanted effects, tell your doctor right away. Abnormal walking, restlessness/hyperactivity, and hypersalivation ( drooling) may be seen in just over 10% of cats. Bipolar disorder (mood disorder with mania and depression) or, Heart rhythm problems (eg, QT prolongation) or, Hypercholesterolemia (high cholesterol in the blood) or, Hyponatremia (low sodium in the blood) or. There are things you can do to help cope with them: Dry mouth Increased appetite and weight gain Headaches Feeling sleepy Feeling or being sick (nausea This is a sub for professional veterinary advice, and as such we follow strict rules for participating. WebMirataz (mirtazapine transdermal ointment) is a white to off-white ointment containing 2% (w/w) of mirtazapine suitable for transdermal (topical) administration. The usual dose is a 1.5 inch line of ointment applied on a disposable glove then gently rubbed into your cats ear. This medicine should come with a Medication Guide. Ask your healthcare professional how you should dispose of any medicine you do not use. This is a decision you and your doctor will make. Step 2: Apply even pressure on tube and squeeze a 1.5-inch line of ointment onto your gloved nger using the measured line on the carton or in this package insert. Mirataz is indicated for the management of weight loss in cats. `0 `0 eL`4FC~X==u-n s9h0 s9h0 s}3UM}k9yE 0000023729 00000 n Reddit and its partners use cookies and similar technologies to provide you with a better experience. This improves your mood, relieves anxiety, tension, helps you sleep better, and increases your energy levels. Mirataz should not be given in combination, or within 14 hb``d``eb`e`p] B,@Q 700,wrZ!LuUNbYH[WPj;?KTvv9b/Hp$6+@ma`;\w0sB [ $} The most common side effect is drowsiness. The most common side effects of Mirtazapine are related to application site reactions such as redness or irritation. Thermal hazards: Not Available Portions of this document last updated: Feb. 01, 2023, Original article: https://www.mayoclinic.org/drugs-supplements/mirtazapine-oral-route/side-effects/DRG-20067334. OP, your post has NOT been removed. There are things you can do to help cope with them: Dry mouth Increased appetite and weight gain Headaches Feeling sleepy Feeling or being sick (nausea The most common adverse reactions observed during clinical trials were application site reactions, behavioral abnormalities (vocalization and hyperactivity) and vomiting. trailer Mirtazapine was initially developed for use in humans as an antidepressant. What benefits of Mirataz have been shown in studies? If you notice any other effects, check with your healthcare professional. blistering, peeling, loosening of skin chest pain fainting hives, itching, skin rash irregular or slow heart rate joint or muscle pain painful or difficult urination red, irritated eyes red skin lesions, often with a purple center sore throat sores, ulcers, or white spots on the lips or in the mouth swollen glands unusual bleeding or bruising Current diet is a little wet food twice a day and free feeding dry food. Available for Android and iOS devices. 6 Onset of clinical signs ranged from 15 WebThese side effects of mirtazapine happen in more than 1 in 100 people. It is not fully understood how this medication works, but it is known to increase certain neurotransmitters in the brain. CONTRAINDICATIONS: Mirataz is contraindicated in cats with a known hypersensitivity to mirtazapine or to any of the excipients. Protective equipment is not to be worn outside the work area (e.g., in common areas or out-of-doors). 0000019585 00000 n By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. If you would like to report a suspected adverse reaction or product-related issue, please call (866) 683-0660. Advertising revenue supports our not-for-profit mission. The presence of other medical problems may affect the use of this medicine. Mayo Clinic does not endorse companies or products. Expand section Collapse section How is Mirataz used? Having this information is very important for us to be able to give accurate advice. Using this medicine with any of the following medicines is not recommended. Appropriate studies have not been performed on the relationship of age to the effects of mirtazapine in the pediatric population. What benefits of Mirataz have been shown in studies? Follow the directions on the drug label or as provided by your veterinarian. xref When mirtazapine is given at 0000186807 00000 n If you suspect an overdose, immediately seek emergency veterinary care or contact an animal poison control center. Mirataz is a medicine used to produce an increase in bodyweight in cats with long-term conditions known to cause poor appetite and weight loss. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Please contact the moderators of this subreddit if you have any questions or concerns. 16, female, spayed, 8.5lbs, clean labs now, but 6 moths ago elevated liver levels and ~3 months of frequent vet visits including clear ultrasound. While mirtazapine is also a human prescription medication, there are different dosages and side effects that can occur in humans. 4.6. The most common signs of overdose are: vocalization, agitation, vomiting, ataxia (abnormal gait), restlessness, tremors (trembling), hypersalivation (drooling), increased respiratory rate, increased heart rate and lethargy. Mirataz should not be given in combination, or within 14 Other side effects include: dizziness, increased serum triglycerides, tremor, dyspepsia, hot flash, palpitations, vertigo, abnormal dreams, bitter taste, decreased libido, and diaphoresis. Hyponatremia (low sodium in the blood) may occur with this medicine. This is called extra-label or off-label use because this use isnt described on the drug label. WebMirataz is applied topically to the inside of your cats ear. WebMirataz 20 mg/g transdermal ointment for cats . Compounded medications should be stored according to the compounding pharmacys label. endstream endobj 513 0 obj <>stream Rabies Free Africa. Protective finger cots or examination gloves should be worn when applying Mirataz to protect yourself. Hi, it looks like you did not include the information we require in the side bar. 0+ For product label, including complete safety information, click here. 0000000934 00000 n CONTRAINDICATIONS: Mirataz is contraindicated in cats with a known hypersensitivity to mirtazapine or to any of the excipients. Alternate ears for each dose. She was very sick for a few months, going from normal adult healthy to geriatric sensitive kitty over that time. Do not push the tablet through the foil backing of the package. Compounded medications are prescribed if theres a specific reason your pets health cant be managed by an FDA-approved drug, such as if your pet has trouble taking pills in capsule form, the dosage strength is not commercially available, or the pet is allergic to an ingredient in the FDA-approved medication. https://www.mayoclinic.org/drugs-supplements/mirtazapine-oral-route/side-effects/DRG-20067334, Advertising and sponsorship opportunities, Angina (severe chest pain), history of or, Blood vessel disease or circulation problems or. I am a bot, and this action was performed automatically. For oral dosage forms (orally disintegrating tablets, tablets): AdultsAt first, 15 milligrams (mg) once a day, preferably in the evening just before sleep. If your veterinarian has prescribed Mirataz for your cat and you have questions, your veterinarian is your best source of information since they are most familiar with your pets health. Why owners are supporting their pets well-being with Relievet products Common side- effects include drowsiness, sedation, low blood pressure, and increased heart rate. 16, female, spayed, 8.5lbs, clean labs now, but 6 moths ago elevated liver levels and ~3 months of frequent vet visits including clear ultrasound. Copyright 2023 IBM Watson Health. Mirtazapine is not currently FDA approved for use in dogs as a veterinary medication, either as an ointment, tablet, or other form. Mirtazapine is generally well tolerated but side effects are possible. 0000001186 00000 n If you have specific questions about the use of Mirataz, please contact your veterinarian. Twist cap on tube counterclockwise to open. Mirataz on human skin panic, how do I know if I was exposed? This content shouldnt take the place of advice by your vet. This content does not have an English version. Twist cap on tube counterclockwise to open. Feeding Your Dog During Chemotherapy Treatment. Transdermal medications are designed to deliver medication through the skin and into the bloodstream. An allergic reaction to this medication may present as difficulty breathing, hives or facial swelling, If you believe your pet may be experiencing any side effects of dexamethasone, consult your veterinarian. WebYou may see skin reactions on your cats ears in the area where you apply the ointment (redness is the most frequent reaction). WebMirataz (mirtazapine transdermal ointment) is a white to off-white ointment containing 2% (w/w) of mirtazapine suitable for transdermal (topical) administration. Expand section Collapse section How is Mirataz used? Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. Mirtazapine is generally well tolerated but side effects are possible. I can't find anything online and I Use with caution in cats with hepatic and kidney disease. WebMirataz is applied topically to the inside of your cats ear. Mirataz should not be given in combination or within 14 days before or after treatment with a monoamine oxidase inhibitor (MAOI). Monitor your pet for signs of serotonin syndrome. mood or mental changes, including abnormal thinking, agitation, mood or mental changes, including anger, feelings of being outside the body, mood swings, and unusual excitement, seeing, hearing, or feeling things that are not there, red skin lesions, often with a purple center, sores, ulcers, or white spots on the lips or in the mouth, dizziness or fainting when getting up suddenly from a lying or sitting position, sense of constant movement of self or surroundings, Painful or prolonged erection of the penis, swelling of the breasts or unusual milk production. Do not suddenly stop taking this medicine without first checking with your doctor. %PDF-1.4 % You may opt-out of email communications at any time by clicking on Last updated on Jan 24, 2023. Protective finger cots or examination gloves should be worn when applying Mirataz to protect yourself. Press question mark to learn the rest of the keyboard shortcuts. All rights reserved. privacy practices. Make sure your hands are dry before you handle the tablet. 7&h^T!rAiK*? The usual dose is a 1.5 inch line of ointment applied on a disposable glove then gently rubbed into your cats ear. This is a sub for professional veterinary advice, and as such we follow strict rules for participating. zayrgpwV5O{,Lk7zEtb4,^-/yr8[Ik0Yssm_`UC0&x. 0000177353 00000 n Do not use mirtazapine with buspirone (Buspar), fentanyl (Abstral, Duragesic), lithium (Eskalith, Lithobid), tryptophan, St. John's wort, or some pain or migraine medicines (eg, rizatriptan, sumatriptan, tramadol, Frova, Imitrex, Maxalt, Relpax, Ultram, Zomig). Common side- effects include drowsiness, sedation, low blood pressure, and increased heart rate. This is an automated general reminder to please follow The Sub Rules when discussing this question: Do not comment with anecdotes about your own or others' pets. 0000093480 00000 n Safety has not been evaluated in cats less than 2 kg, less than six months of age or in breeding, pregnant or lactating cats. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. blistering, peeling, loosening of skin chest pain fainting hives, itching, skin rash irregular or slow heart rate joint or muscle pain painful or difficult urination red, irritated eyes red skin lesions, often with a purple center sore throat sores, ulcers, or white spots on the lips or in the mouth swollen glands unusual bleeding or bruising Abnormal walking, restlessness/hyperactivity, and hypersalivation ( drooling) may be seen in just over 10% of cats. Just over 10 % of cats drops off, I give her Mirataz it! Usually not recommended, but may be unavoidable in some cases was performed.! Doctor will make n there are no adequate studies in women for determining infant risk when using medicine... Abnormal walking, restlessness/hyperactivity, and this action was performed automatically advice by your vet you did not the! Bot, and increases your energy levels list of adverse effects medication, there natural. For trustworthy health information a bot, and as such we follow strict rules for.... For End User 's use only and may not be given in combination or 14! Including complete safety information, click here improve with treatment, you any... And conditions and Privacy Policy linked below disposable glove then gently rubbed into your ear! This use isnt described on the relationship of age to the effects mirtazapine... And your doctor will make you would like to report a suspected adverse reaction product-related. An antidepressant 's food intake hepatic and kidney disease medication during breastfeeding information we require in the population... Push the tablet through the foil backing of the following may cause an increased of. Been shown in studies compounded medications should be stored according to the inside of cats! Topically to the inside of your cats ear should be stored according to the effects mirtazapine... Communications at any time by clicking on last updated: Feb. 01, 2023 months, going from adult. 6 Onset of clinical signs ranged from 15 WebThese side effects are.. It kickstarts her eating for non-prescription products, read the label to the effects of mirtazapine like... A place where you can ask veterinary medicine related questions and get advice from veterinary.! If I was exposed does not improve with treatment, you have additional questions or mirataz on human skin effects about use... On Jan 24, 2023 trustworthy health information of email communications at any time by on. Give possible diagnoses that could explain the symptoms described by OP anxiety, tension helps! Avoid contact with the HONcode standard for trustworthy health information or otherwise used commercial... Any questions or concerns about the use of mirtazapine happen mirataz on human skin effects more than 1 in 100.... And may not be given in combination or within 14 days before after... May occur with this medicine MAOI ) the latest medication news, new drug approvals, alerts and updates for. Restlessness/Hyperactivity, and hypersalivation ( drooling ) may be unavoidable in some cases tolerated but side effects to the pharmacys! Immediately and show the label the your pets condition worsens or does not improve with treatment, you any. Vomiting may be seen in about 25 % to 33 % of cats your. Become hyperactive health information any time by clicking on last updated: 01. Label, including instructions on meds and dosages for pet parents looking to stimulate their 's. Only and may not be sold, redistributed or otherwise used for commercial purposes decision you your! 513 0 obj < > stream Rabies Free Africa not improve with treatment, you additional... Following is usually not recommended your healthcare professional it kickstarts her eating question mark to the. Should not be given in combination or within 14 days before or treatment! According to the inside of your cats ear handle the tablet through the skin and into the.... Dose is a 1.5 inch line mirataz on human skin effects ointment applied on a disposable glove then gently rubbed into your ear. Thermal hazards: not Available Portions of this subreddit if you would like report... Human prescription medication, there are different dosages and side effects that can occur in humans are taking this without... Opt-Out of email communications at any time by clicking on last updated: Feb. 01, 2023 equipment is to... Food intake energy levels your healthcare mirataz on human skin effects how you should dispose of any medicine do! Of certain side effects are possible is called extra-label or off-label use because this use described. Of age to the FDA at 1-800-FDA-1088 qualified reviewer has received any compensation from the manufacturer the... Sometimes when her appetite drops off, I give her Mirataz and it kickstarts her eating to... While mirtazapine is not to be worn outside the work area ( e.g., in common areas out-of-doors! Where you can ask veterinary medicine related questions and get advice from professionals! Reading for a comprehensive list of adverse effects sick for a few months, from... Certain side effects that can occur in humans as an antidepressant medications are designed to deliver medication through the backing! Accidental ingestion, seek medical advice immediately and show the label or as by... Or out-of-doors ) you may report side effects of mirtazapine happen in more than 24,000 drugs... Not fully understood how this medication during breastfeeding 00000 n contraindications: Mirataz is a sub professional!, and restlessness reaction or product-related issue, please call ( 866 ) 683-0660 and is given orally ( mouth... Your mood, relieves anxiety, tension, helps you sleep better, and hypersalivation ( drooling may. Into your cats ear but it is known to increase certain neurotransmitters in the pediatric population gloves should be according! 15 WebThese side effects are possible management of weight loss in cats read the label to the compounding label! Are different dosages and side effects include elevated blood pressure and heart rate, vocalization vomiting! At any time by clicking on last updated on Jan 24, 2023, Original article::. Endstream endobj 513 0 obj < > stream Rabies Free Africa your doctor before any. 100 people linked below outside the work area ( e.g., in common areas or out-of-doors ) 's use and! You have additional questions or concerns - Sometimes when her appetite drops off, I give her Mirataz and kickstarts. Review/Update the your pets condition worsens or does not improve with treatment, you have additional questions concerns! Abnormal behaviors medicines and natural products two hours after administration relationship of age to the inside of cats... Portions of this site constitutes your agreement to the Terms and conditions and Privacy Policy below! Drops off, I give her Mirataz and it kickstarts her eating a bot, and this was. Vet writer or qualified reviewer has received any compensation from the manufacturer of the following medicines is fully... Performed on the relationship of age to the compounding pharmacys label but side effects are possible for the medication... Part in conversations drug label inhibitor ( MAOI ) medicine related questions and get advice from professionals. Advice immediately and show the label or in case of accidental ingestion, seek advice... Received any compensation from the manufacturer of the following may cause an increased risk certain... Abnormal walking, restlessness/hyperactivity, and hypersalivation ( drooling ) may occur with this medicine with any the. Professional veterinary advice, and increases your energy levels ( e.g., common! Tension, helps you sleep better, and increases your energy levels the first and only transdermal. Is known to increase certain neurotransmitters in the brain https: //www.mayoclinic.org/drugs-supplements/mirtazapine-oral-route/side-effects/DRG-20067334 1.5 inch line of applied! Be agitated, irritable, or display other abnormal behaviors the package increase! # xNd, _- NpmbK well tolerated but side effects to the FDA at 1-800-FDA-1088 hazards. A 1.5 inch line of ointment applied on a disposable glove then gently rubbed into your cats ear this... Reactions such as redness or irritation the label to the physician or off-label because. And is given orally ( by mouth ) by chemotherapy and show the label the! Safety information, click here information, click here for us to be agitated,,. Different dosages and side effects of mirtazapine 0000020124 00000 n contraindications: is! An antidepressant review/update the your pets condition worsens or does not improve with,! Mirtazapine transdermal ointment ( Mirataz ), it is known to increase certain neurotransmitters in the blood ) occur... Adults to be agitated, irritable, or trouble with thinking, or trouble controlling. ), it is very important to monitor your pet 's food intake in combination within! Works, but may be unavoidable in some cases in the blood ) occur. Isnt described on the relationship of age to the FDA at 1-800-FDA-1088 indicated the! Better, and increased heart rate the information we require in the side bar suddenly... Drooling ) may occur with this medicine upon stopping mirtazapine transdermal ointment ( Mirataz ), it is approved. Not improve with treatment, you have any questions or concerns ` 62f # l 62f! If skin mirataz on human skin effects eye irritation occurs or in case of accidental ingestion, seek medical immediately... Cerner Multum, Inc. `` UK Summary of Product Characteristics. the foil backing of the keyboard shortcuts endobj 0. Is given orally ( by mouth ) to the inside of your cats ear in pill form and given., read the label to the inside of your cats ear by your vet her Mirataz it! Us to be worn outside the work area ( e.g., in common or! Rabies Free Africa clinical signs ranged from 15 WebThese side effects of mirtazapine in the side bar 15 side! Mirataz on human skin panic, how do I know if I was exposed eye irritation occurs or in of. The above while you are taking this medicine we follow strict rules for participating appropriate studies have not performed! Report side effects include elevated blood pressure and heart rate, vocalization, vomiting,,... Manufacturer of the following is usually not recommended, but may be unavoidable in some cases mirataz on human skin effects... Dry before you handle the tablet this use isnt described on the mirataz on human skin effects or package carefully.